Lara Dotto, Mateus de Azevedo Kinalski, Pablo Soares Machado, Gabriel Kalil Rocha Pereira, Rafael Sarkis-Onofre, Mateus Bertolini Fernandes Dos Santos
OBJECTIVE: This study aimed to assess the characteristics of different designs of systematic reviews (SRs) registered in the International Prospective Register of Systematic Reviews (PROSPERO) about COVID-19. METHODS: The search was performed in the PROSPERO database using the strategy proposed by the database and considered only human studies. The last date of the search was April 27, 2020. Full text of all records was accessed, and data were extracted by a single researcher, which was further double-checked by another researcher...
February 17, 2021: Journal of Evidence-based Medicine
Alicja Zientara, Anja-Rebeka Domenghino, Igor Schwegler, Hans Bruijnen, Annelies Schnider, Markus Weber, Stefan Gutknecht, Nicolas Attigah
BACKGROUND: Mesenteric ischemia is associated with poor outcome and high overall mortality. The aim was to analyze an interdisciplinary treatment approach of vascular and visceral specialists focusing on the in-hospital outcome and follow-up in patients with acute and acute-on-chronic mesenteric ischemia. METHODS: From 2010 until 2017, 26 consecutive patients with acute or acute on chronic mesenteric ischemia were treated by an interdisciplinary team. Data were prospectively collected and retrospectively evaluated...
February 18, 2021: BMC Surgery
Izaskun Balciscueta, Ferran Barberà, Javier Lorenzo, Susana Martínez, Maria Sebastián, Zutoia Balciscueta
BACKGROUND: Outpatient laparoscopic cholecystectomy has proven to be a safe and cost-effective technique; however, it is not yet a universally widespread procedure. The aim of the study was to determine the predictive factors of outpatient laparoscopic cholecystectomy failure. METHOD: A systematic review and meta-analysis was performed according to Preferred Reporting Items for Systematic Reviews and Meta-analysis methodology. MEDLINE, Cochrane Library, Ovid, and ISRCTN Registry were searched...
February 5, 2021: Surgery
Steven Morrison, Dale Han
The vast majority of patients newly diagnosed with melanoma present with clinically localized disease, and sentinel lymph node biopsy (SLNB) is a standard of care in the management of these patients, particularly in intermediate thickness cases, in order to provide important prognostic data. However, SLNB also has an important role in the management of patients with other subtypes of melanoma such as thick melanomas, certain thin melanomas, and specific histologic variants of melanoma such as desmoplastic melanoma...
February 9, 2021: Current Treatment Options in Oncology
Christopher A Lewis-Lloyd, Eleanor M Pettitt, Alfred Adiamah, Colin J Crooks, David J Humes
BACKGROUND: Colorectal cancer has the second highest mortality of any malignancy and venous thromboembolism is a major post-operative complication. OBJECTIVE: Determine the variation in incidence of venous thromboembolism following colorectal cancer resection. DATA SOURCES: Following PRISMA and MOOSE guidelines (PROSPERO, ID: CRD42019148828), Medline and Embase databases were searched from database inception to August 2019 including 3 other registered medical databases...
January 18, 2021: Diseases of the Colon and Rectum
Stacy A Mandras, Hirsch S Mehta, Anjali Vaidya
Pulmonary hypertension (PH) is classified into 5 clinical subgroups: pulmonary arterial hypertension (PAH), PH due to left-sided heart disease, PH due to chronic lung disease, chronic thromboembolic PH (CTEPH), and PH with an unclear and/or multifactorial mechanisms. A range of underlying conditions can lead to these disorders. Overall, PH affects approximately 1% of the global population, and over half of patients with heart failure may be affected. Cardiologists are therefore likely to encounter PH in their practice...
September 2020: Mayo Clinic Proceedings
Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population-based cancer occurrence. Incidence data (through 2017) were collected by the Surveillance, Epidemiology, and End Results Program; the National Program of Cancer Registries; and the North American Association of Central Cancer Registries. Mortality data (through 2018) were collected by the National Center for Health Statistics. In 2021, 1,898,160 new cancer cases and 608,570 cancer deaths are projected to occur in the United States...
January 2021: CA: a Cancer Journal for Clinicians
Laura K Krecko, Tatiana Hoyos Gomez, John E Scarborough, Hee Soo Jung
BACKGROUND: Gallbladder perforation is a known morbid sequela of acute cholecystitis, yet evidence for its optimal management remains conflicting. This study compares outcomes in patients with perforated cholecystitis who underwent cholecystectomy at the time of index hospital admission to those who underwent interval cholecystectomy. STUDY DESIGN: A retrospective analysis was conducted of 654 patients from the ACS NSQIP database who underwent cholecystectomy for perforated cholecystitis (2006-2018)...
January 19, 2021: Journal of the American College of Surgeons
Chaolin Huang, Lixue Huang, Yeming Wang, Xia Li, Lili Ren, Xiaoying Gu, Liang Kang, Li Guo, Min Liu, Xing Zhou, Jianfeng Luo, Zhenghui Huang, Shengjin Tu, Yue Zhao, Li Chen, Decui Xu, Yanping Li, Caihong Li, Lu Peng, Yong Li, Wuxiang Xie, Dan Cui, Lianhan Shang, Guohui Fan, Jiuyang Xu, Geng Wang, Ying Wang, Jingchuan Zhong, Chen Wang, Jianwei Wang, Dingyu Zhang, Bin Cao
BACKGROUND: The long-term health consequences of COVID-19 remain largely unclear. The aim of this study was to describe the long-term health consequences of patients with COVID-19 who have been discharged from hospital and investigate the associated risk factors, in particular disease severity. METHODS: We did an ambidirectional cohort study of patients with confirmed COVID-19 who had been discharged from Jin Yin-tan Hospital (Wuhan, China) between Jan 7, 2020, and May 29, 2020...
January 8, 2021: Lancet
Francis Sutherland, Chad G Ball, Jennifer Schendel, Elijah Dixon
We sought to determine if lateral-inferior traction on the Hartmann pouch could produce bile duct kinking and subsequent misinterpretation of the space on the left side of the bile duct as the hepatobiliary triangle. Once traction was applied, we measured the angle between the cystic duct and inferior gallbladder wall hepatobiliary triangle) in 76 cases, and the angle between the common bile duct and common hepatic duct (porta hepatis "triangle") in 41 cases. The mean angles were significantly different (hepatobiliary triangle mean 68...
January 7, 2021: Canadian Journal of Surgery. Journal Canadien de Chirurgie
C Ann Vitous, Mary E Byrnes, Ana De Roo, Sara M Jafri, Pasithorn A Suwanabol
OBJECTIVE: This qualitative study explored the impact of postoperative complications on surgeons and their well-being. BACKGROUND: Complications are an inherent component of surgical practice. Although there have been extensive efforts to reduce postoperative complications, the impact of complications on surgeons have not been well-studied. Surgeons are often left to process their own emotional responses to these complications, the effects of which are not well characterized...
January 11, 2021: Annals of Surgery
Moises Auron, Marina Y Duran Castillo, Omar Felipe Duenas Garcia
Nonobstetric surgery during pregnancy should be avoided if possible, but when surgery is required, an obstetrician should be part of the perioperative team. In general, preoperative assessment is similar regardless of whether a woman is pregnant, but cardiovascular, pulmonary, hematologic, and renal changes of pregnancy can increase surgical risk and must be taken into account. Special management considerations include pregnancy-associated laboratory changes, timing of surgery, anesthesia choice, intubation precautions, patient positioning, preoperative blood typing, intraoperative fetal monitoring, and venous thromboembolism prophylaxis...
December 31, 2020: Cleveland Clinic Journal of Medicine
Lawrence O Gostin, Daniel A Salmon, Heidi J Larson
No abstract text is available yet for this article.
December 29, 2020: JAMA
Alicia A C Waite, David O Hamilton, Roberto Pizzi, Walter Ageno, Ingeborg D Welters
COVID-19 was first described in late 2019 and has since developed into a pandemic affecting more than 21 million people worldwide. Of particular relevance for acute care is the occurrence of COVID-19-associated coagulopathy (CAC), which is characterised by hypercoagulability, immunothrombosis and venous thromboembolism, and contributes to hypoxia in a significant proportion of patients. This review describes diagnosis and treatment of CAC in the emergency department and in intensive care. We summarise the pathological mechanisms and common complications of CAC such as pulmonary thrombosis and venous thromboembolic events and discuss current strategies for thromboprophylaxis and therapeutic anti-coagulation in the acute care setting...
December 2020: Thrombosis and Haemostasis
Manoj Sivan, Sharon Taylor
No abstract text is available yet for this article.
December 23, 2020: BMJ: British Medical Journal
Erica L Mitchell
No abstract text is available yet for this article.
January 2021: Journal of Vascular Surgery
Valerie Smith, Declan Devane, Alistair Nichol, David Roche
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the strain of coronavirus that causes coronavirus disease 2019 (COVID-19) can cause serious illness in some people resulting in admission to intensive care units (ICU) and frequently, ventilatory support for acute respiratory failure. Evaluating ICU care, and what is effective in improving outcomes for these patients is critical. Care bundles, a small set of evidence-based interventions, delivered together consistently, may improve patient outcomes...
December 21, 2020: Cochrane Database of Systematic Reviews
Richard M Pino, Jaskaran Singh
No abstract text is available yet for this article.
December 17, 2020: Anesthesiology
Simon R Mucha, Siddharth Dugar, Keith McCrae, Douglas Joseph, John Bartholomew, Gretchen L Sacha, Michael Militello
Severe COVID-19 illness is associated with intense inflammation, leading to high rates of thrombotic complications that increase morbidity and mortality. Markedly elevated levels of D-dimer with normal fibrinogen levels are the hallmark laboratory findings of severe COVID-19-associated coagulopathy. Prophylaxis against venous thromboembolism is paramount for all hospitalized patients with COVID-19, with more aggressive prophylaxis and screening recommended for critically ill patients with D-dimer levels above 3...
December 15, 2020: Cleveland Clinic Journal of Medicine
Anne F Peery, Aasma Shaukat, Lisa L Strate
Colonic diverticulitis is a painful gastrointestinal disease that recurs unpredictably and can lead to chronic gastrointestinal symptoms. Gastroenterologists commonly care for these patients. The purpose of this clinical practice update is to provide practical and evidence-based advice for diverticulitis management. We reviewed systematic reviews, meta-analyses, randomized controlled trials, and observational studies to develop 14 best practices. In brief, computed tomography is often necessary to make a diagnosis...
December 3, 2020: Gastroenterology
2020-12-09 16:18:15
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