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Top Papers for 2018—Gastroenterology

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100 papers 25 to 100 followers Top Papers for 2018 - Gastroenterology
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https://read.qxmd.com/read/29756596/hepatic-encephalopathy-classification-and-treatment
#1
Jasmohan S Bajaj
No abstract text is available yet for this article.
April 2018: Journal of Hepatology
https://read.qxmd.com/read/29653941/guidelines-for-the-investigation-of-chronic-diarrhoea-in-adults-british-society-of-gastroenterology-3rd-edition
#2
Ramesh P Arasaradnam, Steven Brown, Alastair Forbes, Mark R Fox, Pali Hungin, Lawrence Kelman, Giles Major, Michelle O'Connor, Dave S Sanders, Rakesh Sinha, Stephen Charles Smith, Paul Thomas, Julian R F Walters
Chronic diarrhoea is a common problem, hence clear guidance on investigations is required. This is an updated guideline from 2003 for the investigations of chronic diarrhoea commissioned by the Clinical Services and Standards Committee of the British Society of Gastroenterology (BSG). This document has undergone significant revision in content through input by 13 members of the Guideline Development Group (GDG) representing various institutions. The GRADE system was used to appraise the quality of evidence and grading of recommendations...
August 2018: Gut
https://read.qxmd.com/read/30099106/when-to-resume-direct-oral-anticoagulants-following-gastrointestinal-bleeding
#3
EDITORIAL
Moe H Kyaw, Francis K L Chan
No abstract text is available yet for this article.
August 9, 2018: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/29653741/easl-clinical-practice-guidelines-for-the-management-of-patients-with-decompensated-cirrhosis
#4
(no author information available yet)
No abstract text is available yet for this article.
August 2018: Journal of Hepatology
https://read.qxmd.com/read/30195459/acute-on-chronic-liver-failure-vs-traditional-acute-decompensation-of-cirrhosis
#5
REVIEW
Thierry Gustot, Richard Moreau
No abstract text is available yet for this article.
September 7, 2018: Journal of Hepatology
https://read.qxmd.com/read/29980848/the-state-of-the-art-on-treatment-of-crohn-s-disease
#6
REVIEW
Hai Yun Shi, Siew Chien Ng
Crohn's disease (CD) is a chronic, progressive, and destructive disease of the gastrointestinal tract. Although its incidence appears to be stable or decreasing in most countries in the North America and Europe, the incidence is rising rapidly in Asian countries. Immunomodulators and biologics are increasingly used to avoid long-term bowel damage and subsequent disability. Therapeutic drug monitoring facilitates optimizing thiopurines and anti-TNFs use. New biologic agents targeting various pathological pathways of CD are blooming in recent years, and the high cost of biologics and expiration of patents for several biologic agents have driven the utility of biosimilars for CD treatment...
September 2018: Journal of Gastroenterology
https://read.qxmd.com/read/29427735/a-new-marker-for-severity-of-alcoholic-hepatitis
#7
EDITORIAL
Fernando Calmet, Paul Martin
No abstract text is available yet for this article.
August 2018: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/30273751/aga-clinical-practice-update-on-surgical-risk-assessment-and-perioperative-management-in-cirrhosis-expert-review
#8
REVIEW
Patrick G Northup, Lawrence S Friedman, Patrick S Kamath
No abstract text is available yet for this article.
March 2019: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/29973706/refractory-ascites-in-liver-cirrhosis
#9
Danielle Adebayo, Shuet Fong Neong, Florence Wong
Ascites, a common complication of liver cirrhosis, eventually becomes refractory to diuretic therapy and sodium restriction in ∼10% of patients. Multiple pathogenetic factors are involved in the development of refractory ascites, which ultimately lead to renal hypoperfusion and avid sodium retention. Therefore, renal dysfunction commonly accompanies refractory ascites. Management includes continuation of sodium restriction, which needs frequent reviews for adherence; and regular large volume paracentesis of 5 L or more with albumin infusions to prevent the development of paracentesis-induced circulatory dysfunction...
January 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/29501369/acute-pancreatitis-guideline
#10
Seth Crockett, Yngve Falck-Ytter, Sachin Wani, Timothy B Gardner
No abstract text is available yet for this article.
March 2018: Gastroenterology
https://read.qxmd.com/read/29510130/new-eosinophilic-esophagitis-concepts-call-for-change-in-proton-pump-inhibitor-management-before-diagnostic-endoscopy
#11
EDITORIAL
Eunice Odiase, Armond Schwartz, Rhonda F Souza, Jason Martin, Vani Konda, Stuart Jon Spechler
No abstract text is available yet for this article.
April 2018: Gastroenterology
https://read.qxmd.com/read/30429590/diagnosis-and-management-of-primary-biliary-cholangitis
#12
Zobair M Younossi, David Bernstein, Mitchell L Shiffman, Paul Kwo, W Ray Kim, Kris V Kowdley, Ira M Jacobson
Primary biliary cholangitis (PBC) is a chronic, cholestatic, autoimmune disease with a variable progressive course. PBC can cause debilitating symptoms including fatigue and pruritus and, if left untreated, is associated with a high risk of cirrhosis and related complications, liver failure, and death. Recent changes to the PBC landscape include a name change, updated guidelines for diagnosis and treatment as well as new treatment options that have recently become available. Practicing clinicians face many unanswered questions when managing PBC...
January 2019: American Journal of Gastroenterology
https://read.qxmd.com/read/29336434/acg-clinical-guideline-alcoholic-liver-disease
#13
Ashwani K Singal, Ramon Bataller, Joseph Ahn, Patrick S Kamath, Vijay H Shah
Alcoholic liver disease (ALD) comprises a clinical-histologic spectrum including fatty liver, alcoholic hepatitis (AH), and cirrhosis with its complications. Most patients are diagnosed at advanced stages and data on the prevalence and profile of patients with early disease are limited. Diagnosis of ALD requires documentation of chronic heavy alcohol use and exclusion of other causes of liver disease. Prolonged abstinence is the most effective strategy to prevent disease progression. AH presents with rapid onset or worsening of jaundice, and in severe cases may transition to acute on chronic liver failure when the risk for mortality, depending on the number of extra-hepatic organ failures, may be as high as 20-50% at 1 month...
February 2018: American Journal of Gastroenterology
https://read.qxmd.com/read/29406201/proton-pump-inhibitors-review-of-emerging-concerns
#14
REVIEW
Avinash K Nehra, Jeffrey A Alexander, Conor G Loftus, Vandana Nehra
First introduced in 1989, proton pump inhibitors (PPIs) are among the most widely utilized medications worldwide, both in the ambulatory and inpatient clinical settings. The PPIs are currently approved by the US Food and Drug Administration for the management of a variety of gastrointestinal disorders including symptomatic peptic ulcer disease, gastroesophageal reflux disease, and nonulcer dyspepsia as well as for prevention of gastrointestinal bleeding in patients receiving antiplatelet therapy. PPIs inhibit gastric acid secretion, and the most commonly associated adverse effects include abdominal pain, diarrhea, and headache...
February 2018: Mayo Clinic Proceedings
https://read.qxmd.com/read/29306520/guidelines-for-sedation-and-anesthesia-in-gi-endoscopy
#15
Dayna S Early, Jenifer R Lightdale, John J Vargo, Ruben D Acosta, Vinay Chandrasekhara, Krishnavel V Chathadi, John A Evans, Deborah A Fisher, Lisa Fonkalsrud, Joo Ha Hwang, Mouen A Khashab, V Raman Muthusamy, Shabana F Pasha, John R Saltzman, Amandeep K Shergill, Brooks D Cash, John M DeWitt
No abstract text is available yet for this article.
February 2018: Gastrointestinal Endoscopy
https://read.qxmd.com/read/29557943/discontinuing-long-term-ppi-therapy-why-with-whom-and-how
#16
REVIEW
Laura Targownik
Proton pump inhibitors (PPIs) are among the most widely used class of drugs prescribed over the long term in all of clinical medicine with 8-10% of ambulatory adults have been prescribed a PPI in the past 30 days. However, numerous studies have raised doubts about the long term safety of PPI use. The purpose of this review is threefold: (i) To provide an overview of the current evidence demonstrating associations between PPI use and adverse health outcomes and the likelihood of the associations being causal (Why?); (ii) To be able to identify long-term PPI users in whom the intensity of PPI therapy could be reduced or in whom PPIs could be eliminated outright (Who?); and (iii) To provide strategies on how to reduce or stop chronic PPI therapy while maintaining symptom control and reducing the risk for symptom or upper GI disease recurrence (How?)...
April 2018: American Journal of Gastroenterology
https://read.qxmd.com/read/29628281/easl-clinical-practice-guidelines-management-of-hepatocellular-carcinoma
#17
(no author information available yet)
No abstract text is available yet for this article.
July 2018: Journal of Hepatology
https://read.qxmd.com/read/30144956/easl-clinical-practice-guidelines-on-nutrition-in-chronic-liver-disease
#18
(no author information available yet)
A frequent complication in liver cirrhosis is malnutrition, which is associated with the progression of liver failure, and with a higher rate of complications including infections, hepatic encephalopathy and ascites. In recent years, the rising prevalence of obesity has led to an increase in the number of cirrhosis cases related to non-alcoholic steatohepatitis. Malnutrition, obesity and sarcopenic obesity may worsen the prognosis of patients with liver cirrhosis and lower their survival. Nutritional monitoring and intervention is therefore crucial in chronic liver disease...
August 22, 2018: Journal of Hepatology
https://read.qxmd.com/read/30002466/current-management-of-hepatic-encephalopathy
#19
Chathur Acharya, Jasmohan S Bajaj
No abstract text is available yet for this article.
November 2018: American Journal of Gastroenterology
https://read.qxmd.com/read/29949497/prophylaxis-against-upper-gastrointestinal-bleeding-in-hospitalized-patients
#20
REVIEW
Deborah Cook, Gordon Guyatt
New England Journal of Medicine, Volume 378, Issue 26, Page 2506-2516, June 2018.
June 28, 2018: New England Journal of Medicine
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